Center for Single Cell Biology

Zepp, J. A. et al. Genomic, epigenomic, and biophysical cues controlling the emergence of the lung alveolus. Science 371, doi:10.1126/science.abc3172 (2021).


Uzun, Y., Wu, H. & Tan, K. Predictive modeling of single-cell DNA methylome data enhances integration with transcriptome data. Genome Research 31, 101-109, doi:10.1101/gr.267047.120 (2021).


Melenhorst, J. J. et al. Decade-long leukaemia remissions with persistence of CD4+ CAR T cells. Nature 2022, 1-7, doi:10.1038/s41586-021-04390-6 (2022).


Hu, Y., Peng, T., Gao, L. & Tan, K. CytoTalk: De novo construction of signal transduction networks using single-cell transcriptomic data. Sci. Adv 7 (2021).


Chen, G. M. et al. Integrative bulk and single-cell profiling of premanufacture t-cell populations reveals factors mediating long-term persistence of car t-cell therapy. Cancer Discovery 11, 2186-2199, doi:10.1158/2159-8290.CD-20-1677 (2021).


Chen, C. et al. Single-cell multi-omics reveals elevated plasticity and stem-cell-like blasts relevant to the poor prognosis of KMT2A-rearranged leukemia. Blood, doi:10.1101/2020.12.06.413930 (2021).


Zhu, Q. et al. Developmental trajectory of prehematopoietic stem cell formation from endothelium. Blood 136, 845-845, doi:10.1182/BLOOD.2020004801 (2020).


Zhang, Y., Kim, M. S., Reichenberger, E. R., Stear, B. & Taylor, D. M. ScEDAR: A scalable Python package for single-cell RNA-seq exploratory data analysis. PLoS Computational Biology 16, doi:10.1371/journal.pcbi.1007794 (2020).


Yu, W., Uzun, Y., Zhu, Q., Chen, C. & Tan, K. scATAC-pro: a comprehensive workbench for single-cell chromatin accessibility sequencing data. Genome Biology 21, doi:10.1186/S13059-020-02008-0 (2020).


Rozenblatt-Rosen, O. et al. The Human Tumor Atlas Network: Charting Tumor Transitions across Space and Time at Single-Cell Resolution. Cell 181, 236-249, doi:10.1016/j.cell.2020.03.053 (2020).


Taylor, D. M. et al. The Pediatric Cell Atlas: Defining the Growth Phase of Human Development at Single-Cell Resolution. Developmental Cell 49, 10-29, doi:10.1016/j.devcel.2019.03.001 (2019).


Peng, T., Zhu, Q., Yin, P. & Tan, K. SCRABBLE: Single-cell RNA-seq imputation constrained by bulk RNA-seq data. Genome Biology 20, doi:10.1186/s13059-019-1681-8 (2019).


Packer, J. S. et al. A lineage-resolved molecular atlas of C. elegans embryogenesis at single cell resolution HHS Public Access. Science 365, doi:10.5061/dryad.7tg31p7 (2019).


Hu, P. et al. Single-nucleus transcriptomic survey of cell diversity and functional maturation in postnatal mammalian hearts. Genes and Development 32, 1344-1357, doi:10.1101/gad.316802.118 (2018).